The distribution of alternative agents for targeted radiotherapy within human neuroblastoma spheroids
نویسندگان
چکیده
منابع مشابه
Targeted radiotherapy for neuroblastoma.
Background Biologically targeted radiotherapy is an established treatment for thyrotoxicosis and thyroid cancer. The principle is to take advantage of the ability of the thyroid and, to a lesser degree, diVerentiated thyroid carcinoma to concentrate and retain iodide. In this situation the radionuclide (I) in ionic form is a natural substrate for targeting thyroid tissue, thus acting both as th...
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Tumor spheroid model for the biologically targeted radiotherapy of neuroblastoma micrometastases.
Neuroblastoma is a pediatric malignancy with a poor prognosis at least partly attributable to an early pattern of dissemination. New approaches to treatment of micrometastases include targeted radiotherapy using radiolabeled antibodies or molecules which are taken up preferentially by tumor cells. Multicellular tumor spheroids (MTS) resemble micrometastases during the avascular phase of their d...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1991
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1991.93